Arab Journal of Gastroenterology
Volume 10, Issue 4 , Pages 135-140 , December 2009

A study of duodenal intraepithelial lymphocytic population and its relation to coeliac disease in a cohort of patients in the Nile delta of Egypt

  • Hanan AlSaeid Alshenawy

      Affiliations

    • Department of Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt
    • ,
  • Eiman Adel Hasby

      Affiliations

    • Department of Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt
    • ,
  • Asem Ahmed Elfert

      Affiliations

    • Department of Tropical Medicine and Infectious Diseases, Faculty of Medicine, Tanta University, Tanta, Egypt
    • Corresponding Author InformationCorresponding author. Tel.: +20 124378188.

Received 29 April 2009 ,Accepted 29 September 2009.

References 

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  2. Catassi C, Fasano A. Celiac disease. Curr Opin Gastroenterol. 2008;24(6):687–691
  3. Biagi F, Luinetti O, Campanella J, et al. Intraepithelial lymphocytes in the villous tip: do they indicate potential coeliac disease?. J Clin Pathol. 2004;57(8):835–839
  4. Marsh MN, Crowe PT. Morphology of the mucosal lesion in gluten sensitivity. Bailliére’s Clin Gastroenterol. 1995;9(2):273–293
  5. Memeo L, Jhang J, Hibshoosh H, et al. Duodenal intraepithelial lymphocytosis with normal villous architecture: common occurrence in H. pylori gastritis. Mod Pathol. 2005;18(8):1134–1144
  6. Zimmer KP, Naim H, Weber P, et al. Targeting of gliadin peptides, CD8, alpha/beta-TCR and gamma/delta-TCR to Golgi complexes and vacuoles within celiac disease enterocytes. FASEB J. 1998;12(13):1349–1357
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  10. Fry L, Seah PP, McMinn RM, et al. Lymphocytic infiltration of epithelium in diagnosis of gluten-sensitive enteropathy. Br Med J. 1972;3(5823):371–374
  11. Goldstein NS. Proximal small-bowel mucosal villous intraepithelial lymphocytes. Histopathology. 2004;44(3):199–205
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  13. Hayat M, Cairns A, Dixon MF, et al. Quantitation of intraepithelial lymphocytes in human duodenum: what is normal?. J Clin Pathol. 2002;55(5):393–394
  14. Goldstein NS, Underhill J. Morphologic features suggestive of gluten sensitivity in architecturally normal duodenal biopsy specimens. Am J Clin Pathol. 2001;116(1):63–71
  15. Mino M, Lauwers GY. Role of lymphocytic immunophenotyping in the diagnosis of gluten-sensitive enteropathy with preserved villous architecture. Am J Surg Pathol. 2003;27(9):1237–1242
  16. Kakar S, Nehra V, Murray JA, et al. Significance of intraepithelial lymphocytosis in small bowel biopsy samples with normal mucosal architecture. Am J Gastroenterol. 2003;98(9):2027–2033
  17. Ernst PB, Takaishi H, Crowe SE. Helicobacter pylori infection as a model for gastrointestinal immunity and chronic inflammatory diseases. Dig Dis. 2001;19(2):104–111
  18. Santarelli L, Gabrielli M, Santoliquido A, et al. Interaction between Helicobacter pylori infection and untreated coeliac disease on gastric histological pattern. Scand J Gastroenterol. 2006;41(5):532–535
  19. Bedoya A, Garay J, Sanzon F, et al. Histopathology of gastritis in Helicobacter pylori-infected children from populations at high and low gastric cancer risk. Hum Pathol. 2003;34(3):206–213

PII: S1687-1979(09)00270-6

doi: 10.1016/j.ajg.2009.09.007

Arab Journal of Gastroenterology
Volume 10, Issue 4 , Pages 135-140 , December 2009

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