Arab Journal of Gastroenterology
Volume 10, Issue 4 , Pages 151-154, December 2009

Metastatic gastrointestinal stromal tumours of the stomach: A report on two cases and literature review

Department of Surgery, M.G.M. Medical College & M.Y.H. Group of Hospitals, Indore, Madhya Pradesh 452 001, India

Received 7 October 2009; accepted 19 October 2009. published online 10 December 2009.

Abstract 

Gastrointestinal stromal tumours (GISTs) are mesenchymal tumours of the gastrointestinal tract, accounting for approximately 1% of gastric malignancies. We report on two cases of large malignant irresectable stromal tumours of the stomach with presence of concomitant distant metastases, treated palliatively, and followed by adjuvant imatinib therapy. The rarity lies in the presence of distant as well as lymph node metastases. The literature on this topic is reviewed.

Keywords: Gastrointestinal stromal tumour, Lymph node metastases, Imatinib, c-Kit

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PII: S1687-1979(09)00273-1

doi:10.1016/j.ajg.2009.10.005

Arab Journal of Gastroenterology
Volume 10, Issue 4 , Pages 151-154, December 2009