Arab Journal of Gastroenterology
Volume 10, Issue 4, Supplement , Pages S10-S11 , April 2010

Hepatic progenitor cells in acute and chronic liver disease: Clinical aspects

  • Frederik Nevens

      Affiliations

    • Department of Hepatology, University Hospital Gasthuisberg, KU Leuven, Belgium
    • Corresponding Author InformationCorresponding author. Address: Department of Hepatology, University Hospital Gasthuisberg, KU Leuven, B-3000 Leuven, Belgium. Tel.: +32 16 344299; fax: +32 16 344387.
    • ,
  • Aezam Katoonizadeh

      Affiliations

    • Department of Hepatology, University Hospital Gasthuisberg, KU Leuven, Belgium
    • Department of Pathology, University Hospital Gasthuisberg, KU Leuven, Belgium
    • ,
  • Tania Roskams

      Affiliations

    • Department of Pathology, University Hospital Gasthuisberg, KU Leuven, Belgium

References 

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  2. Roskams T, De Vos R, Van Eyken P, Miyazaki H, Van Damme B, Desmet V. Hepatic OV-6 expression in human liver disease and rat experiments: evidence for hepatic progenitor cells in man. Hepatology. 1998;29:455–463
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  4. Roskams T. Progenitor cells involvement in cirrhotic human liver diseases: from controversy to consensus. Hepatology. 2003;39:431–434
  5. Haque S, Haruna Y, Saito K, et al. Identification of bipotential progenitor cells in human liver regeneration. Lab Invest. 1996;75:699–705
  6. Roskams T, Libbrecht L, Desmet VJ. Hepatic progenitor cells in diseased human liver. Semin Liver D. 2003;23(4):385–396
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  8. Xiao JC, Ruck P, Adam A, Wang TX, Kaiserling E. Small epithelial cells in human liver cirrhosis exhibit features of hepatic stem-like cells: immunohistochemical, electron microscopic and immunoelectron microscopic findings. Histopathology. 2003;42:141–149
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  15. Katoonizadeh A, Decaestecker J, Wilmer A, Aerts R, Verslype C, Vansteenbergen W, et al. MELD score to predict outcome in adult patients with non-acetaminophen-induced acute liver failure. Liver Int. 2007;329–334
  16. O’Grady JG, Alexander GJ, Hayllar KM, Williams R. Early indicators of prognosis in fulminant hepatic failure. Gastroenterology. 1989;97:439–445
  17. Bernuau J, Goudau A, Polynard T, et al. Multivariate analysis of prognosis in fulminant hepatic failure. Gastroenterology. 1989;97:439–445
  18. Schmidt Le, Dalhoff K. Alpha-fetoprotein is a predictor of outcome in acetaminophen-induced liver failure. Hepatology. 2005;41:26–31
  19. Katoonizadeh A, Nevens F, Verslype C, Pirenne J, Roskams T. Liver regeneration in acute severe liver impairment: a clinicopathological correlation study. Liver Int. 2006;26:1225–1233
  20. Laleman W, Van Landeghem L, Wilmer A, Fevery J, Nevens F. Portal hypertension: from pathophysiology to clinical practice. Liver Int. 2005;25(6):1079–1090
  21. Laleman W, Wilmer A, Evenepoel P, Vander Elst I, Zeegers M, Zaman Z, et al. Effect of the molecular adsorbent recirculating system and Prometheus devices on systemic heamodynamic and vasoactive agents in patients with acute-on-chronic alcoholic liver failure. Crit Care. 2006;10:R108
  22. Laleman W, Wilmer A, Evenepoel P, Verslype C, Fevery J, Nevens F. Review article: non-biological liver support in liver failure. Aliment Pharmacol Ther. 2005;23:351–363
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PII: S1687-1979(09)00317-7

doi: 10.1016/j.ajg.2009.12.010

Arab Journal of Gastroenterology
Volume 10, Issue 4, Supplement , Pages S10-S11 , April 2010

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